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Experimental model of heterotopic ossification in Wistar rats BJMBR
Zotz,T.G.G.; Paula,J.B. de; Moser,A.D.L..
Heterotopic ossification (HO) is a metaplastic biological process in which there is newly formed bone in soft tissues adjacent to large joints, resulting in joint mobility deficit. In order to determine which treatment techniques are more appropriate for such condition, experimental models of induced heterotopic bone formation have been proposed using heterologous demineralized bone matrix implants and bone morphogenetic protein and other tissues. The objective of the present experimental study was to identify a reliable protocol to induce HO in Wistar rats, based on autologous bone marrow (BM) implantation, comparing 3 different BM volumes and based on literature evidence of this HO induction model in larger laboratory animals. Twelve male Wistar albino...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Heterotopic ossification; Autologous bone marrow; Serum alkaline phosphatase.
Ano: 2012 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2012000600004
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Fibrodysplasia ossificans progressiva-like in a cat Arq. Bras. Med. Vet. Zootec.
Crivelenti,L.Z.; Borin,S.; Brum,A.M.; Honsho,D.K..
Fibrodysplasia ossificans progressiva-like (FOP-like) was diagnosed in a young Brazilian cat presenting progressive lameness, pain upon manipulation and inability to extend the hind limbs. Due to poor response to medication described in the literature, only orchiectomy and confinement of the patient were recommended. The patient described here has been observed for four years and the animal is currently in fair condition despite the movement restrictions.
Tipo: Info:eu-repo/semantics/article Palavras-chave: Feline; Myositis ossificans; Heterotopic ossification.
Ano: 2012 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352012000200015
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Influence of transcutaneous electrical stimulation on heterotopic ossification: an experimental study in Wistar rats BJMBR
Zotz,T.G.G.; Paula,J.B. de.
Heterotopic ossification (HO) is a metaplastic biological process in which there is newly formed bone in soft tissues, resulting in joint mobility deficit and pain. Different treatment modalities have been tried to prevent HO development, but there is no consensus on a therapeutic approach. Since electrical stimulation is a widely used resource in physiotherapy practice to stimulate joint mobility, with analgesic and anti-inflammatory effects, its usefulness for HO treatment was investigated. We aimed to identify the influence of electrical stimulation on induced HO in Wistar rats. Thirty-six male rats (350-390 g) were used, and all animals were anesthetized for blood sampling before HO induction, to quantify the serum alkaline phosphatase. HO induction...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Heterotopic ossification; Experimental model; Electrical stimulation; Functional electrical stimulation; Transcutaneous electrical nerve stimulation.
Ano: 2015 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2015001101055
Registros recuperados: 3
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